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Senior Computational Biologist – Early Discovery Immunology

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Description

You will integrate phenomics, transcriptomics, genomics, and proteomics data to nominate targets, validate disease biology, and define precision immunology strategies. You will develop target-discovery methods, collaborate with scientific and engineering partners, and present analyses that inform program decisions.

Responsibilities

  • Evaluate molecular evidence for target nomination and validation
  • Identify novel vulnerabilities in immunology and inflammation disease biology
  • Pilot methods for target discovery, disease biology validation, and patient population hypotheses
  • Define criteria for target data packages and patient population strategy
  • Connect analysis methods with platform and engineering teams
  • Build data packages with cross-functional partners
  • Present data analyses to decision makers and stakeholders

Requirements

  • PhD in a relevant computational field and 3+ years of biotech or pharmaceutical industry experience, or MS in a relevant field and 5+ years of such experience
  • Expertise in immunological diseases and target identification
  • Understanding of patient genetics and pathway druggability
  • Experience applying probabilistic, statistical, or machine learning methods to complex biological or clinical data
  • Python or R
  • Data visualization
  • Cross-functional communication

Benefits

  • Annual bonus
  • Equity compensation
  • Comprehensive benefits package

Skills

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