Executive Director of Chemical Biology

You will set chemical biology strategy, lead multidisciplinary discovery programs, and connect multiomic insights to target identification and chemical probe design. You will manage internal and external chemistry teams, define program priorities and go/no-go criteria, and guide the integration of computational and generative design approaches.

Responsibilities

• Set chemical biology strategy using the multiomics platform
• Build, manage, and mentor a team of multiomics chemists
• Manage internal and external CRO chemistry teams and networks
• Execute screening, synthesis, and validation campaigns
• Partner with biology, target identification, structural biology, and computational drug design teams
• Define program strategy and go/no-go criteria with senior leadership
• Represent the team in portfolio reviews, governance meetings, and external technical discussions
• Contribute to IP strategy and business development activities

Requirements

• PhD in chemical biology, chemistry, or a related field
• 10+ years of relevant industry experience
• Demonstrated people leadership
• Hands-on experience designing chemical probes
• Experience with selective inhibitors, molecular glue degraders, PROTACs, covalent chemistry, activity-based chemistry, or photoaffinity chemistry
• Ability to deconvolute phenotypic hits using chemoproteomics or equivalent target identification methods
• Experience building and scaling a chemical biology function
• Experience setting multi-year technical strategy
• Experience managing chemists and cross-functional project teams, including CRO teams
• Executive-level communication skills

Benefits

• Annual bonus
• Equity compensation
• Comprehensive benefits package